Recent Posters and Scientific Meeting Presentations
Poster for presentation at the International Symposium on NeuroVirology in Atlanta, GA, November 2019
- Contribution of cerebrovascular disease to brain atrophy in virally suppressed older HIV-infected participants. Milanini, et al.
Oral presentation at the 10th International Workshop on HIV & Aging in New York, NY, October 2019
- The relationships between depression, social isolation, and loneliness among aging PLWH and cognitive impairment. Dobbins et al.
Posters for presentation at the 26th Conference on Retroviruses and Opportunistic Infections in Seattle, WA, March 2019
- Inflammatory Plasma Biomarkers Correlate with Diffusion Tensor Imaging in Chronic HIV. Chang, et al.
- Early Inflammatory Profiles in Long-Term Virally Suppressed Women Predict Cognition. Dastgheyb, et al.
- Longitudinal Phenotyping of Declarative Memory among Women Living with HIV. Fitzgerald, et al.
- Capturing DNA Methylation Changes in Monocytes When Initiating ART in Acute HIV. Corley, et al.
- Neuropsychiatric Outcomes Before and After Initiation of ART in Acute HIV. Chan, et al.
- Minimal Incidence of CSF Escape After Initiation of ART in Acute HIV Infection. Handoko, et al.
- Resting-State Connectivity Associates with Depression Symptoms in Acute HIV. Philippi, et al.
- Depression is a Stronger Predictor of Executive Dysfunction in HIV+ Women than Men. Rubin, et al.
Poster for presentation at the Alzheimer's Association International Conference in Chicago, IL, July 2018
- Longitudinal Cognitive and Brain Volumetric Changes to Distinguish Alzheimer's Disease from HIV Encephalopathy in HIV over Age 60 Years. Milanini, et al.
Posters for presentation at the 25th Conference on Retroviruses and Opportunistic Infections in Boston, MA, March 2018
- Intact Structural and Functional Brain Imaging in Acute HIV. Samboju, et al.
- Predictors of HIV-Related Cognitive Impairment in East Africa. Milanini, et al.
- CSF and Blood HIV RNA Relationship in Acute HIV is linked to CD4/CD8 Ratio. Chan, et al.
- Longitudinal Cognitive Outcomes after Treatment in Acute HIV Infection. Chan, et al.
- Cerebral Glutathione Metabolism in HIV Infection and Response to ART. Sailasuta, et al.
- Neurologic Stability with Brief Analytic Treatment Interruption after Early ART. Hellmuth, et al.
- Depression is Independently Associated with Near Doubling of HIV Viral Load. Meffert, et al.
Oral presentation at the 8th International Workshop on HIV & Aging in New York, NY, October 2017
- Cognitive Impairment in Symptomatic HIV Over age 60. Javandel et al.
Posters for presentation at the 24th Conference on Retroviruses and Opportunistic Infections in Seattle, WA, February 2017
- The African Cohort Study: HIV Drug Resistance - A Unique Perspective Across Four African Countries. Danboise, et al.
- Plasma Soluble CD163 is Suppressed upon Early ART Initiation in Acute HIV Infection. D'Antoni, et al.
- Heightened Systemic and CNS Immune Activation in Acute HIV Infection with Syphilis. Chan, et al.
- Limitations of the International HIV Dementia Scale in the Current Era. Milanini, et al.
- CSF S100B and CX3CR1 Monocytes in Acute HIV Infection Predict Putamen Atrophy. Ndhlovu et al.
- CNS Immune Activation Persists in Acute and Chronic HIV Despite Extended cART. Hellmuth, et al.
- CNS Monitoring of cART Interruption in Individuals Treated during Fiebig I Acute HIV. Chan, et al.
- MRS Measures Associate with Impaired Neuropsychological Performance in Acute HIV. Hellmuth, et al.
- Monocyte Activation is Associated with Cognition in Supressed HIV-Infected Women. Imp, et al.
- Early Macrophage Independent Inflammation and SHIV-RNA in CNS in a Rhesus SHIV Model. Hsu, et al.
- Cognitive Trajectories Over 4 Years Among HIV-Infected Women with Optimal Viral Suppression. Rubin, et al.
- Deep Sequencing Reveals Rare CNS Compartmentalization in Acute HIV-1 Infection. Sirijatuphat, et al.
Poster for presentation at the International Society of Neurovirology, Toronto, Canada, October 2016
- Discriminant analysis of neuropsychological testing differentiates HIV-associated Neurocognitive Disorder (HAND) from Mild Cognitive Impairment (MCI) due to Alzheimer's disease in HIV over age 60. Milanini, et al.
Posters for presentation at the 23rd Conference on Retroviruses and Opportunistic Infections in Seattle, WA, February 2016
- Psychiatric Symptoms are Common in Acute HIV and Correlate with Disease Biomarkers. Hellmuth, et al.
- Neurologic Signs and Symptoms Frequently Manifest in Acute HIV Infection. Hellmuth, et al.
- Brain Volumetric Changes After Two Years of ART Initiated During Acute HIV Infection. Kallianpur, et al.
- Male/Female Differences in Cognitive Function in HIV+ Individuals. Maki, et al.
- Peripheral Immune Activation Modulates HIV RNA Entry to CSF in Early Acute Infection. Schuetz, et al.
- Dual Role of Activated and HIV-specific CD8 T cells in CSF during Acute HIV Infection. Trautmann, et al.
- Liver Fibrosis Linked to Cognition in HIV and HCV: The Women’s Interagency HIV Study. Valcour, et al.
- Early CSF Viremia and CNS T Cell Infiltrate in a Non-Accelerated SHIV Infection Model. Vasan, et al.
Poster for presentation at the Infectious Diseases Society of America ID Week, San Diego, CA October 2015
- Evaluation of Aging & HIV in a Rural Ugandan Cohort: Impact & Challenges. CPT Copeland, et al.
Poster for presentation at the International Symposium of Biomedical Imaging in Brooklyn, NY, April 2015
- Mapping Abnormal Subcortical Brain Morphometry in an Elderly HIV+ Cohort. Wade et al.
Poster for presentation at the International AIDS Society annual meeting in Vancouver, Canada, July 2015
- iMap: Creating Maps from Longitudinal MRI Brain Images of Aging HIV Population to Drive HAND Characterization . Pohl et al.
Posters for presentation at the International Society for Neurovirlogy annual meeting in San Diego, California, June 2015
- Loss of CCR2 Expressing Non-Classical Monocytes are Associated with Cognitive Impairment in Antiretroviral Therapy-naive HIV-Infected Thais. Ndhlovu et al.
Posters for presentation at the Organization for Human Brain Mapping annual meeting in Honolulu, Hawaii, June 2015
- Boosting the power to detect HIV effects on brain connectivity using High-Order SVD. Zhan et al.
- A meta-analysis by the ENIGMA-HIV working group: CD4 counts predict subcortical volume loss in HIV-positive individuals. Fouche et al.
- Local brain-volume variation in children with perinatally acquired HIV via tensor-based morphometry. Nir et al.
Posters for presentation at the 22nd Conference on Retroviruses and Opportunistic Infections in Seattle, February 2015
- Astrocyte and microglial activation in acute and chronic HIV pre- and post-cART. M. Peluso et al.
- CD14+ PBMC secrete cytokines linked to HIV-Associated Neurocognitive Disorders. M. Agsalda-Garcia et al.
- Predictors of cognitive performance among HIV-infected patients in East Africa. V Valcour et al.
- Infectious and noninfectious multimorbidity among HIV clinic clients in the African Cohort Study. J Ake et al.
- Acute HIV/CSF plasma RNA ratios are variable and greater than in chronic HIV. J Hellmuth et al.
Posters presentation at the 21st Conference on Retroviruses and Opportunistic Infections in Boston, March 2014
- CNS Outcomes of cART vs. cART plus Maraviroc and Raltegravir Intensification During Acute HIV. V Valcour et al.
- Inflammation in Acute HIV Infection Correlates with Blood and Gut CD4 T-Cell Loss and Viral Burden. N Sandler et al.
- Early ART Initiation Prevents Disruption of the Mucosal Barrier and subsequent T Cell Activation. A Schuetz et al.
- Loss of HIV Serological Markers Following Early Treatment of Acute HIV Infection. M Manak et al.
- Early Monocyte Inflammation among Treatment-Naïve Acute HIV-infected Thai Subjects. L Ndhlovu et al.
- Immediate Antiretroviral Therapy Mitigates the Development of Neuronal Injury in Acute HIV. M Peluso et al.
Oral presentations from CROI 2014
- Immediate Antiretroviral Therapy Mitigates the Development of Neuronal Injury in Acute HIV. M Peluso et al.
- CNS Outcomes of cART vs. cART plus Maraviroc and Raltegravir Intensification During Acute HIV. V Valcour et al.
Publications
Aging, HIV and Cognition
Monocytes, HIV DNA and neuroAIDS Outcomes
International HIV
Acute HIV
Pediatric NeuroAIDS
Reviews
- A neuropathologic diagnosis of Alzheimer's disease in an older adult with HIV-associated neurocognitive disorder. Neurocase. 2018
- Limitations of the international HIV dementia scale in the current era. AIDS. 2018
- Progressive brain atrophy despite persistent viral suppression in HIV over age 60. J Acquir Immune Defic Syndr. 2017
- Psychiatric symptom burden in older people living with HIV with and without cognitive impairment: the UCSF HIV Over 60 cohort study. AIDS Care. 2017
- White matter hyperintensities correlate to cognition and fiber tract integrity in older adults with HIV. J Neurovirol. 2017
- ApoE ε4 is Associated with Cognition, Brain Integrity and Atrophy in HIV Over Age 60. J Acquir Immune Defic Syndr. 2016
- Subcortical shape and volume abnormalities in an elderly HIV+ cohort. Proc SPIE Int Soc Opt Eng. 2015
- Human immunodeficiency virus (HIV) modulates the associations between insulin resistance and cognition in the current combination antiretroviral therapy (cART) era: a study of the Women's Interagency HIV Study (WIHS). J Neurovirol. 2015
- The association of perceived stress and verbal memory is greater in HIV-infected versus HIV-uninfected women. J Neurovirol. 2015
- Geriatric Syndromes in Older HIV-Infected Adults. J Acquir Immune Defic Syndr. 2015
- Interctions between ageing and NeuroAIDS. Curr Opin HIV AIDS. 2015
- The Montreal cognitive assessment to screen for cognitive impairment in HIV patients older than 60 years. J Acquir Immune Defic Syndr. 2014
- Polypharmacy, drug-drug interactions, and potentially inappropriate medications in older adults with human immunodeficiency virus infection. J Am Geriatr Soc. 2014
- Deficits in Self-awareness Impact the Diagnosis of Asymptomatic Neurocognitive Impairment in HIV. AIDS Res Hum Retroviruses. 2013
- Mapping white matter integrity in elderly people with HIV. Hum Brain Mapp. 2013
- Disrupted brain networks in the aging HIV+ population. Brain Connect. 2012
- The Impact of Depressive Symptoms on Neuropsychological Performance Tests in HIV-Infected Individuals: A Study of the Hawaii Aging with HIV Cohort. World J AIDS. 2011
- Cerebrovascular risk factors and brain microstructural abnormalities on diffusion tensor images in HIV-infected individuals. J Neurovirol. 2012
- Summary report from the Human Immunodeficiency Virus and Aging Consensus Project: treatment strategies for clinicians managing older individuals with the human immunodeficiency virus. Work Group for HIV and Aging Consensus Project. J Am Geriatr Soc. 2012
- Evaluating cognitive impairment in the clinical setting: practical screening and assessment tools. Top Antivir Med. 2011
- Associations of cardiovascular variables and HAART with cognition in middle-aged HIV-infected and uninfected women. J Neurovirol. 2011
- Screening for cognitive impairment in human immunodeficiency virus. Clin Infect Dis. 2011
- Insulin resistance and cognition among HIV-infected and HIV-uninfected adult women: the Women's Interagency HIV Study. AIDS Res Hum Retroviruses. 2012
- Impact of cerebrovascular disease on cognitive function in HIV-infected patients. J Acquir Immune Defic Syndr. 2011
- The Effects of Age and HIV on Neuropsychological Performance. J Int Neuropsychol Soc. 2011
- Aging exacerbates extrapyramidal motor signs in the era of highly active antiretroviral therapy. J Neurovirol. 2008
- Frequency of apolipoprotein E4 among older compared with younger HIV patients: support for detrimental effect of E4 on survival. Proc Natl Acad Sci U S A. 2008
- Cortical atrophy and white matter hyperintensities in HIV: the Hawaii Aging with HIV Cohort Study. J Stroke Cerebrovasc Dis. 2008
- Small-vessel vascular disease in human immunodeficiency virus infection: the Hawaii aging with HIV cohort study. Cerebrovasc Dis. 2007
- Neuropsychological test profile differences between young and old human immunodeficiency virus-positive individuals. J Neurovirol. 2007
- Insulin resistance is associated with cognition among HIV-1-infected patients: the Hawaii Aging With HIV cohort. J Acquir Immune Defic Syndr. 2006
- Lowest ever CD4 lymphocyte count (CD4 nadir) as a predictor of current cognitive and neurological status in human immunodeficiency virus type 1 infection--The Hawaii Aging with HIV Cohort. J Neurovirol. 2006
- Diabetes, insulin resistance, and dementia among HIV-1-infected patients. J Acquir Immune Defic Syndr. 2005
- Age, apolipoprotein E4, and the risk of HIV dementia: the Hawaii Aging with HIV Cohort. J Neuroimmunol. 2004
- Higher frequency of dementia in older HIV-1 individuals: the Hawaii Aging with HIV-1 Cohort. Neurology. 2004
- Symptomatic distal sensory polyneuropathy in HIV after age 50. Neurology. 2004
Monocytes, HIV DNA and neuroAIDS Outcomes
- CNS reservoirs for HIV: implications for eradication. J Virus Erad. 2015
- HIV DNA in CD14+ reservoirs is associated with regional brain atrophy in patients naive to combination antiretroviral therapy. AIDS. 2014
- HIV DNA reservoir increases risk for cognitive disorders in cART-naive patients. PLOS One. 2013
- Peripheral blood HIV DNA is associated with atrophy of cerebellar and subcortical gray matter. Neurology. 2013
- Ethnic differences in epidermal nerve fiber density. Muscle & nerve. 2013
- Antiretroviral monocyte efficacy score linked to cognitive impairment in HIV. Antivir Ther. 2012
- Cognitive performance related to HIV-1-infected monocytes. J Neuropsychiatry Clin Neurosci. 2012
- Failure to clear intra-monocyte HIV infection linked to persistent neuropsychological testing impairment after first-line combined antiretroviral therapy. J Neurovirol. 2012
- HIV DNA in circulating monocytes as a mechanism to dementia and other HIV complications. J Leukoc Biol. 2010
- Amount of HIV DNA in peripheral blood mononuclear cells is proportional to the severity of HIV-1-associated neurocognitive disorders. J Neuropsychiatry Clin Neurosci. 2009
- HIV DNA and cognition in a Thai longitudinal HAART initiation cohort: the SEARCH 001 Cohort Study. Neurology. 2009
- Expression of monocyte markers in HIV-1 infected individuals with or without HIV associated dementia and normal controls in Bangkok Thailand. J Neuroimmunol. 2008
- HIV proviral DNA associated with decreased neuropsychological function. J Neuropsychiatry Clin Neurosci. 2007
- HIV DNA and dementia in treatment-naïve HIV-1-infected individuals in Bangkok, Thailand. Int J Med Sci. 2006
- Circulating proviral HIV DNA and HIV-associated dementia. AIDS. 2005
International HIV
- Brain Imaging and Neurodevelopment in HIV-Uninfected Thai Children Born to HIV-Infected Mothers. Pediatr Infect Dis J. 2015
- Association between brain volumes and HAND in cART-naive HIV+ individuals in Thailand. J Neurovirol. 2015
- Trail Making Test A improves performance characteristics of the International HIV Dementia Scale to identify symptomatic HAND. J Neurovirol. 2013
- Impaired neurocognitive function among HIV-infected Thais on stable antiretroviral therapy for more than 7 years. J Int AIDS Soc. 2012
- Development of normative neuropsychological performance in Thailand for the assessment of HIV-associated neurocognitive disorders. J Clin Exp Neuropsychol. 2012
- Frequency and characteristics of HIV-associated sensory neuropathy among HIV patients in Bangkok, Thailand. J Acquir Immune Defic Syndr. 2008
- Neuropsychological abnormalities in patients with dementia in CRF 01_AE HIV-1 infection. Neurology. 2007
Acute HIV
- Structural and functional brain imaging in acute HIV. Neuroimage Clin. 2018
- Neurologic signs and symptoms frequently manifest in acute HIV infection. Neurology. 2016
- Neurological Response to cART vs. cART plus Integrase Inhibitor and CCR5 Antagonist Initiated during Acute HIV. PLoS One. 2015
- Absence of Cerobrospinal Fluid Signs of Neuronal Injury Before and After Immediate Antiretroviral Therapy in Acute HIV Infection. J Infect Dis. 2015
- Change in brain magnetic resonance spectroscopy after treatment during acute HIV infection. PLoS One. 2012
- Central nervous system viral invasion and inflammation during acute HIV infection. J Infect Dis. 2012
- Impact of multi-targeted antiretroviral treatment on gut T cell depletion and HIV reservoir seeding during acute HIV infection. PLoS One. 2012
Pediatric NeuroAIDS
- Neurodevelopmental outcomes in HIV-exposed-uninfected children versus those not exposed to HIV. AIDS Care. 2014
- Cognitive Function and Neurodevelopmental Outcomes in HIV-Infected Children Older than One Year of Age Randomized to Early Versus Deferred Antiretroviral Therapy: The PREDICT Neurodevelopmental Study. Pediatr Infect Dis J. 2013
Reviews
- Differentiating HIV-Associated Neurocognitive Disorders from Alzheimer's Disease: An Emerging Issue in Geriatric NeuroHIV. Curr HIV/AIDS Rep. 2017
- Cognitive Impairment and Persistent CNS Injury in Treated HIV. Curr HIV/AIDS Rep. 2016
- Pathogenesis of HIV in the central nervous system. Curr HIV/AIDS Rep. 2011
- Updated research nosology for HIV-associated neurocognitive disorders. Neurology. 2007
- HIV infection and dementia in older adults. Clin Infect Dis. 2006
- HIV-associated dementia, mitochondrial dysfunction, and oxidative stress. Mitochondrion. 2004
- Cognitive impairment in older HIV-1-seropositive individuals: prevalence and potential mechanisms. AIDS. 2004